Fig. 5

Fig. 5 The tmod4^trg skeletal muscle has impaired force generation. (A) Peak active force at optimal length in tmod4^trg is significantly lower than that of siblings (n=6). (B) During single-twitch contraction, the half-time (t_1/2) of contraction is similar in tmod4^trg and siblings, however, the relaxation time is significantly prolonged in tmod4^trg (n=6). (C) Length–active force curves show steeper ascending limb in tmod4^trg (red) than in siblings (blue) (n=5). Force is normalised to the maximal active force at optimal length (L_opt), and length is normalised to L_opt. Data are means ± s.e.m., **P<0.01, ***P<0.001.