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Fig. 4
notch3fh332 mutants have a deficit of pericytes. (A-F) pdgfrb+ brain pericytes in wild-type (WT) and mutant fish. Arrowheads, pdgfrb+ pericytes in the mutant larvae; open arrowheads, reduced vessel branching in forebrain and hindbrain. All images show confocal projections of whole brains from lateral view with dorsal up and anterior to the left. (G) Quantification of pdgfrb+ brain pericytes at different time points during embryonic and larval development in wild-type and mutant fish (ne25 each). *P<0.001 by Student’s two-tailed t-test. Scale bar: 200 μm.
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