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Fig. 6
Loss of prdm12b has a modest effect on hindbrain, but not spinal, motor neurons. (A–Q) Expression of Isl1/2 (A–D, K, L), olig2 (E–H), olig2:egfp (I, J), Isl1/2 together with hoxb1a:egfp (M, N) or Alcama (O–Q) in wild-type (A, C, E, F, I, K, M, O), PTB MO-injected (B, D, G, H, J, L, N, Q), or control MO-injected (P) embryos at 24 hpf (A–H) or 50 hpf (I–Q). Embryos are shown in lateral (A, B, I, J) or dorsal (C, D, K–Q) view with anterior to the left, or in cross section (E–H) with dorsal to the top. All scale bars are 35 μm, except I, J are 100 μm and E, H are 50 μm. RB – Rohon-Beard cells, MN – motor neurons, and (n)=cranial nerves.
Reprinted from Developmental Biology, 390, Zannino, D.A., Downes, G.B., Sagerström, C.G., prdm12b specifies the p1 progenitor domain and reveals a role for V1 interneurons in swim movements, 247-60, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.