ZFIN Image: Eroglu et al., 2014, Fig. S8

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Figure Caption

Fig. S8

HSBP1 morpholino-injected embryos show aberrant expression of genes involved in neurodevelopment.

In situ hybridization analyses showing the expression of the indicated markers in control MO-injected or HSBP1 MO-injected embryos at the indicated times post fertilization. The markers were as follows: Anf (a-b), Eng2 (c-h), Krox-20 (i-n), Ntl (o-r), and Hlx1 (s-t). Morphant phenotypes were more than 90%. n=40. Embryos are dorsal view (a-I; o-p) or lateral view (m-n; q-t). For in situ hybridization analyses a total of 3000 embryos were injected and 200 embryos were used per probe. No nonspecific hybridization was observed with sense probes (data not shown). Embryos were photographed using a SPOT camera mounted on a dissecting microscope. Mag. 40x.

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Acknowledgments

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Reprinted from Developmental Biology, 386(2), Eroglu, B., Min, J.N., Zhang, Y., Szurek, E., Moskophidis, D., Eroglu, A., and Mivechi, N.F., An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development, 448-460, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.