ZFIN Image: Samson et al., 2013, Fig. S7

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Figure Caption

Fig. S7

Knockdown of 3-OST-7 affects expression pattern of versican but does not alter expression patterns of other heart differentiation markers at 48 hpf. ISH for versican, an AV myocardium-localized marker, showed ectopic expression in ventricular myocardium of 3-OST-7 morphants (A and B). Expression of anf, a marker for chamber myocardium, was comparable between control and 3-OST-7 morphants (C and D). Tie2 expression, assessed in Tg(tie2:EGFP) embryos, was normally expressed in 3-OST-7 morphant AV endocardium (F) and is similar to control (E). Control groups (A and C) were injected with control 3-OST-3Z MO, control (E) was uninjected. V, ventricle; At, atrium; red arrows point to AV; dashed white lines outline the heart.

Acknowledgments

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