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Fig. 2
dlx5a and mmp9 are genes downstream of evx1.
(A) Whole mount ISH shows levels of dlx5a expression and mmp9 expression are reduced in the evx1-morpholino (evx1-MO) injected side compared with the evx1-mismatch (evx1-MM) injected side, while the level of col10a1b expression is unchanged. (B) Whole mount ISH on evx1-/- mutants displays similar results seen in the evx1-MO injected fins, except that a stronger reduction in dlx5a and mmp9 is observed. Arrows identify regions of the fin where staining is present and/or expected (i.e. in the cases where reduced evx1 influences expression levels).
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