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Fig. 6 Genetic interaction between col22a1 and itga7. Synergistic genetic interactions between zebrafish col22a1 (COLXXII) and itga7 (integrin α7β1) (A), lama2 (laminin α2) (B) or dag1 (dystroglycan) (C), and between lama2 and itga7 or dag1 (D), and mean frequencies of muscle detachment phenotype observed in morphants. Images show lateral views of 72 hpf embryo tail musculature stained with phalloidin-rhodamine after injection, alone or in combination, of sub-phenotypic doses of morpholinos against col22a1, itga7 (A), lama2 (B) and dag1 (C). Scale bars: 50 μm. Data are mean±s.e.m. (n=3). ***P<0.001; **P<0.01.
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