|
Fig. S7 Androgens induce angiogenesis in intact and regenerating female pectoral fins. (A,C,E,G,I) Intact fins of T-treated females develop BTs following 4 dot (A). BTs are vascularized 5 dot (black arrow) (C). (E,G,I) 6-8dot, BTs mature and appear similar to 3 males. (B,D,F,H,J) Regenerating pectoral fins of T-treated females undergo two waves of blood vessel regeneration. (B) The central artery located between the hemirays regenerates in the first wave. (D,F,H,J) Initiated at 5 dpa, the second wave of angiogenesis travels in a proximal-distal fashion parallel to the hemiray (red arrowheads), occurring alongside BT regeneration. Amputation plane is indicated by white vertical lines. Scale bars= 50μm (shown in A).