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Fig. 3
Premature alterations of the testis tissue of tert mutant zebrafish. (A) Representation of testis cell distribution from the wild-type and tert mutant genotype according to their telomere length. Medium fluorescence intensity (MFI) is indicated for each genetic background. The same trend was observed in the three independent experiments. (B) Representative image of zebrafish testis (n=3) from tert+/+ and tert-/- backgrounds at 4, 8 and 18 months old (200×). Asterisks in panel 6 indicate atrophic tubules, and arrowheads atrophic stroma.
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Full text @ Dis. Model. Mech.