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Figure Caption
Fig. S11 Human Eaf function is evolutionary conserved in regulating Wnt/β-catenin signaling. (A,B) In zebrafish embryos injected with human EAF1 or EAF2 mRNA, dkk1 (A) and frzb (B) displayed enhanced expression. (C) Overexpression of human EAF1 or EAF2 did not affect co-transfected human β-catenin stability. (D) Overexpression of human EAF1 or EAF2 did not change the endogenous active β-catenin protein level. (E-G) Ectopic expression of human TCF4 (E), human c-JUN (F) and human AXIN (G) after co-transfection with human EAF1 or EAF2 into the HEK 293T cell line.
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