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Fig. s3 Zic6 morpholino knock-down experiments. (A–C), The morphants developed the curled-down body axis, the abnormal hindbrain reminiscent of that in mib mutants, cardiac edema. (D), Zic6 morpholino knock-down experiments (Exp 1 to 3) and rescue experiment (Exp 4). The roof plate “gap” phenotype was scored at 72 hpf in separate experiments (Exp 5 to 8, the numbers of assessed embryos are shown in brackets).
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