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Fig. S3 Embryos resolve cerebral-vascular defects and resume normal development. (A-H) Representative bright-field photomicrographs of zebrafish embryos soaked in DMSO or 0.5 mg/L ATV and stained with OD at various developmental stages. Black arrows indicate areas of hemorrhage and blue arrows indicate sinus venosus. Anterior is to the left and dorsal to the top. Scale bar = 200 μm.
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Reprinted from Developmental Biology, 373(2), Eisa-Beygi, S., Hatch, G., Noble, S., Ekker, M., and Moon, T.W., The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway, 258-266, Copyright (2013) with permission from Elsevier. Full text @ Dev. Biol.