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Fig. 7 Spatial distribution of zfmor at 24 and 48 hpf.
Lateral views (A-D, G-J), dorsal views (E-F, K-L). zfmor was found in the telencephalon, diencephalon, midbrain (optic tectum), MHB, hindbrain, spinal cord, eye and somites. The expression in embryos exposed to cocaine exposure was increased in the optic tectum and MHB (Asterisk and arrow, respectively). At 48 hpf, zfmor was expressed to a similar extent to what was observed at 24 hpf, and also in the MLF, notochord, pectoral flipper and heart. Cocaine induced a decrease in zfmor levels in the telencephalon and MLF (arrow and asterisk, respectively). Abbreviations: T: telencephalon; Mb: midbrain, Hb: hindbrain, D: diencephalon, N: notochord; S: somite; pf: pectoral flipper; H: heart. Scale bar: 200 μm in A (Applies to B, G and H) and 250 μm in C (Applies to D, E, F, I, J, K and L).