Fig. 8

Fig. 8 [1–232] human atxn7 fragment can rescue differentiation defects of cerebellar neurons in 0.3 pmol MOzatxn7^SPL morphant.

Dorsal views of dissected brains from 5 dpf 1 pmol mmMOzatxn^AUG (A, A′ and A′′) and 0.3 pmol MOzatxn7^SPL morphants (B, B′ and B′′) and age-matched 0.3 pmol MOzatxn7^SPL morphant co-injected with human atxn7 mRNA (2 fmol) (C, C′ and C′′). Pav7 immunostaining of Purkinje cells (A, B and C) and Vglut1 immunostaining of granule cells (A′, B′ and C′). Anterior is to the left. Merge images of the photographs A and A′ (A′′), B and B′ (B′′), and C and C′ (C′′).