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Fig. S3
Related to Figure 4. Motility reprogramming
(A) Knock-down of dnd inhibits bleb formation in PGCs. (B) Down regulation of Annexin A5b in dnd morpholino treated PGCs restores bleb formation. (C) Somatic cells treated with control morpholino (red cells) and non-treated cells (green) show no protrusive activity. (D) Cells receiving the motility module (as in Figure 4F) show protrusive activity. Arrowheads point at the positions of protrusion formation and asterisks label reference somatic cells. See also Movie S3 and S5.
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Reprinted from Developmental Cell, 23(1), Goudarzi, M., Banisch, T.U., Mobin, M.B., Maghelli, N., Tarbashevich, K., Strate, I., van den Berg, J., Blaser, H., Bandemer, S., Paluch, E., Bakkers, J., Toli-Nørrelykke, I.M., and Raz, E., Identification and Regulation of a Molecular Module for Bleb-Based Cell Motility, 210-218, Copyright (2012) with permission from Elsevier. Full text @ Dev. Cell