Fig. 7 Thyroid development is severely impaired in bcl2l morphant embryos. Lateral views with anterior to the left of 48 hpf embryos. Experimental morpholino is indicated on the top and markers on the left of the figure, percentage (indicating the fraction of the described phenotype) at bottom left of each image. (A)–(E) pax2a staining in control MO (A), in bcl2l MO (B) and (C) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (D) and (E); (F)–(J) pax8 staining in control MO (F), in bcl2l MO (G) and (H) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (I) and (J); (K)–(O) nk2.1a staining in control MO (K), in bcl2l MO (L) and (M) injected embryos and in bcl2l MO and bcl2l mRNA co-injected embryos (N) and (O). Arrows point to thyroid primordium.
Reprinted from Developmental Biology, 366(2), Porreca, I., De Felice, E., Fagman, H., Di Lauro, R., and Sordino, P., Zebrafish bcl2l is a survival factor in thyroid development, 142-152, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.