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Fig. S4
Normal biliary anatomy in ren morphants. (A–B) Confocal projections of cytokeratin immunostaining of livers of 5 dpf cont (A) and ren MO (B)-injected larvae, which appear fairly similar. (C) Quantification of duct properties, including total number of ducts, number of interconnecting ducts, number of terminal ductules, duct length, width, and angle. There is a significant difference (**p d 0.005) only in the number of terminal ductules. Note that these differences are considerably more subtle than those in the V-H+-ATPase mutants and morphants (Fig. 5 and Table 1).
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Reprinted from Developmental Biology, 365(2), Eauclaire, S.F., Cui, S., Ma, L., Matous, J., Marlow, F.L., Gupta, T., Burgess, H.A., Abrams, E.W., Kapp, L.D., Granato, M., Mullins, M.C., and Matthews, R.P., Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish, 434-444, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.