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Fig. 4
cebpβ Is Expressed within HSPCs in Response to Infection and Is Required for Demand-Driven Granulopoiesis (A) Expression of cebpβ within the AGM of infected larvae, compared with PBS controls at 12 hpi and 2 dpi. (B) Dual WMISH of cebpβ and runx1 within the AGM of infected larvae at 12 hpi. (C) Dual WMISH of cebpβ and lyz within the AGM of infected larvae at 2 dpi. (D) Control MO- and C/ebpβ MO-injected Tg(lyz:EGFP)/Tg(gata1:DsRED) larvae following infection, compared with PBS controls at 2 dpi. Numbers represent frequency of embryos or larvae with displayed phenotype. Scale bar, 100 μm in (D). All views, anterior to left. Abbreviations: DA, dorsal aorta; PCV, posterior cardinal vein. See also Figure S4.