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Fig. 3
Effect of the seahorse mutation on the kinocilia of 4-day-old zebrafish. (A) Numerous kinocilia, labeled by an antiserum against acetylated α-tubulin, protrude from the crista of semicircular canal in a wild-type animal. (B) The kinocilia of a seahorse mutant larva displays enlarged kinocilia, one with a basal swelling. (C) In another mutant animal, several kinocilia are bloated at their bases. (D) A higher-magnification view of one hair cell from a seahorse larva depicts the swollen base of a kinocilium; the arrowhead indicates the position of the hair cell′s apical surface. (Scale bars, 5μm.)
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