ZFIN Image: Liu et al., 2011, Fig. 2

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Figure Caption

Fig. 2

The laterality of heart jogging and looping was randomized in fgfr2c morphants.

The development of heart was followed using Line 544 (cmlc2:EGFP/β-actin2-mCherry) transgenic fish. Normal direction of heart jogging was toward left side (A~C, L-jog). Randomization resulted in abnormal patterns of jogging (D~I, R-jog and mid-jog). Normal heart looping (J~L, D-loop) and abnormal heart looping (M~Q, L-loop and no-loop) were detected in un-injected transgenic line 544 embryos, fgfr2c and fgfr2c-5 mm morphants. All pictures were ventral-anterior view. The bar charts showed the percentage of different types of heart jogging and looping (R). A: atrium, V: ventricle. Left-right axis was indicated as labeled.

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Acknowledgments

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