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Fig. 1
MZmid mutants lack notochords.
(A–C) Protein diagrams of FoxH1 alleles. (D–F) 24 hour post-fertilization (hpf) images of live wild-type and maternal-zygotic FoxH1 mutant embryos. (G–I) Dorsal zooms (2.5× relative magnification) of embryos in D–F at the level of the yolk extension. Red brackets mark the notochord; MZmid mutants lack this structure and exhibit midline-fused somites. (J–L) RNA in situ hybridization for ntl expression in 24 hpf wild-type and maternal-zygotic FoxH1 mutants.
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