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Fig. s1 A-G bugeye mutants show varying degrees of asymmetry in eye size (B-G), with the smaller of the two eyes only occasionally falling within the range of the wild-type eye size to body length ratio (E:B; wild-type E:B < 0.05, bugeye E:B >0.06). For each eye, the E:B is indicated. H In asymmetric eyes of bugeye fish, intraocular pressure (IOP) was elevated only in the enlarged eyes. In TL wild-type, the eye measured for IOP first had a higher value than the second eye measured in the same fish. Black symbols represent the first eye of a fish that was measured for IOP and gray symbols represent the second eye. The vertical bar connecting symbols shows eyes from the same fish. Circles represent normal sized eyes; squares represent enlarged eyes.