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Figure Caption
Fig. 6 runx2b expression responds to cyclopamine treatment at a similar rate as that of ptc1. Fish were treated with cyclopamine or EtOH starting at 72 hpf and then fixed at 76 hpf (A, B, G and H), 78 hpf (C, D, I and J) or 80 hpf (E, F, K and L). Cyclopamine treatment only leads to a strong reduction of runx2b and ptc1 expression after 8 h (F and L). (M) shown the quantification of the number ceratohyal primordia expressing runx2b from (A–F). Please see Fig. 2 for abbreviations and notes.
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Reprinted from Mechanisms of Development, 128(1-2), Felber, K., Croucher, P., and Roehl, H.H., Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish, 141-152, Copyright (2011) with permission from Elsevier. Full text @ Mech. Dev.