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Fig. 4 Role of PC5.1 in lateral line neuromasts development as revealed by alkaline phosphatase staining of larvae injected with either PC5.1 MO-1 or with PC5.1 and p53 morpholino co-injection. The injected larvae at 72–96 hpf were labeled with Di-Asp. Then the larvae were fixed and stained for alkaline phosphatase activity. Both the larvae injected with PC5.1 MO-1 (B) and co-injected with PC5.1 and p53 morpholinos (C, D) show a marked decrease in the number of labeled neuromasts when compared to wild-type larvae (A). Individual neuromasts of the posterior lateral line are indicated by arrows.
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