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Fig. S10
Characterization of the ikaros::gfp zebrafish transgenic line.
(A) Schematic description of the wild-type ikaros locus (upper panel) and the modified locus with insertion of gfp in the second exon. The BAC identification number is given.
(B) Expression of gfp in lymphoid tissues corresponds to endogenous ikaros expression, as revealed by comparative analysis at various time points. ICM, intermediate cell mass; CHT, caudal hematopoietic tissue; the thymus is encircled. Note that the strength of gfp signal in brain structures depends on the exact con-focal plane of analysis. Size bars, 50μm.
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Reprinted from Cell, 138(1), Bajoghli, B., Aghaallaei, N., Hess, I., Rode, I., Netuschil, N., Tay, B.H., Venkatesh, B., Yu, J.K., Kaltenbach, S.L., Holland, N.D., Diekhoff, D., Happe, C., Schorpp, M., and Boehm, T., Evolution of genetic networks underlying the emergence of thymopoiesis in vertebrates, 186-197, Copyright (2009) with permission from Elsevier. Full text @ Cell