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Fig. 7 Injection of wild-type Plk1, kinase-dead mutant, D-box mutant, and PBD domain mutant RNAs (illustrated and marked in Fig. 1A) in wild-type and plk1 morphant embryos. Embryos were injected with various GFP-plk1 RNAs alone (A) or in combination with plk1 MO (B). Embryos were collected at the 18-somite stage and stained with anti-pH3 antibodies (red) to assess the effect of the expression of these RNAs on mitosis. Enlarged images of chromosomes stained with anti-pH3 are shown in the inner box for comparison.
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Reprinted from Developmental Biology, 345(1), Jeong, K., Jeong, J.Y., Lee, H.O., Choi, E., and Lee, H., Inhibition of Plk1 induces mitotic infidelity and embryonic growth defects in developing zebrafish embryos, 34-48, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.