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Fig. S1 Ligand trap signals are NRs specific A Morpholino (MO) against the FSH-tag of the GAL-NR transgene was injected into one-cell stage F3 embryos of LT-PPARγ, RORγ and LT-TRβ. Endogenous and agonistic drug responses were compared between control and MO injected embryos. The upper row shows 48 hpf PPARγ embryos in their chorions, and tail close ups of the same conditions are shown in the middle row. The lower row shows RORγ (F2) or homozygous TRβ F3 embryos in the presence of 250 nM T3 with control or MO injections.
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