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Fig. 8 The nkx6 genes are required to the establishment of the endocrine progenitor pool. A–P: WISHs showing expression at 13 somites of pdx1 (A, E, I and M), neuroD (B, F, J and N), sox4b (C, G, K and O), and pax6b (D, H, L and P) in control (A–D), nkx6.1 (E–H), nkx6.2 (I–L), and nkx6.1/nkx6.2 (M–P) morphants. Except D, H, L and P which are lateral, all views are ventral; anterior part to the left. Scale: 20 μm. Q–T: quantitative analysis of the number of pdx1- (Q), neurod- (R), sox4b- (S) and pax6b-expressing cells (T) at 13 somites in control and nkx6 morphants (the horizontal line represents the mean). The presented data were collected from at least two reproducible and independent experiments. In the figure, the superior titles are "Pdx1", "NeuroD", "Sox4b" rather than "Pdx1N", "euroDS" and "ox4b". You will find this figure, at slightly reduced size, at the following address: https://edc.ulg.ac.be/merci/fig8_b5c4cd3b3b244ee41533_.eps.
Reprinted from Developmental Biology, 340(2), Binot, A.C., Manfroid, I., Flasse, L., Winandy, M., Motte, P., Martial, J.A., Peers, B., and Voz, M.L., Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells, 397-407, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.