ZFIN Image: Zhang et al., 2010, Fig. S4

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Figure Caption

Fig. S4 Phenotypic comparison of brain ventricle expansion defects in different zebrafish ion pump Atp1a1-deficient or cell polarity mutants. Arrowhead indicates location of the hindbrain ventricle in a WT embryo at 30 hpf. Hindbrain ventricular shapes are outlined in red. Sections of immunohistochemical stainings of the brain neuroepithelium show that Cldn5a colocalizes apically together with atypical protein kinase C (aPKC) at the inner ventricular (V) surface at 30 hpf (arrows; Left Inset indicates the cross-sectional plane through the hindbrain region). Localization of Cldn5a and aPKC is affected in nok^m520/mpp5a and ome^m289/crb2 cell polarity mutants. (Scale bar: 50 μm.)

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Full text @ Proc. Natl. Acad. Sci. USA