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Fig. 4 pdlim7 and tbx5 functionally interact during heart development. (A–D) In situ hybridization of 48 hpf embryos with cmlc2. (A) Uninjected wild-type control. (B) Wild-type embryo injected with 75 pg of pdlim7 mRNA. (C) Uninjected hst/+ embryo. (D) hst/+ embryo injected with 75 pg pdlim7 mRNA. (E) Quantification of uninjected and injected embryos with a string-like heart.
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Reprinted from Developmental Biology, 337(2), Camarata, T., Krcmery, J., Snyder, D., Park, S., Topczewski, J., and Simon, H.G., Pdlim7 (LMP4) regulation of Tbx5 specifies zebrafish heart atrio-ventricular boundary and valve formation, 233-245, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.