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Fig. 5

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ZDB-IMAGE-091217-88
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Figures for Komisarczuk et al., 2009
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Fig. 5 Enhancers with reporter protein expression in fgf8a-specific patterns. (A) The tetrapod-specific element fgf.hs19 drove GFP expression in the vasculature in zebrafish transgenic lines. (B) Elements that showed a main specific pattern with extra variable domains. Only specific domains are indicated. Element fgf.dr10 was active in the forebrain, midbrain–hindbrain boundary, cerebellum, hindbrain, notochord and apical ectodermal ridge. Element fgf.dr14 had activity in the heart, hindbrain, notochord, branchial arches, otic vesicle, pectoral fin and otic ganglion. Element fgf.dr22 drove GFP expression in epiphysis, forebrain, hindbrain, spinal cord and apical ectodermal ridge. For abbreviations, see Fig. 3; (H) heart, (NC) notochord, (OG) otic ganglion, (V) vasculature. Scale bars = 250 μm.

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Reprinted from Developmental Biology, 336(2), Komisarczuk, A.Z., Kawakami, K., and Becker, T.S., Cis-regulation and chromosomal rearrangement of the fgf8 locus after the Teleost/tetrapod split, 301-312, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.