ZFIN Image: Lee et al., 2009, Fig. S5

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Figure Caption

Fig. S5 A Distinct Role for Notch Signaling in the Formation of Endothelial Progenitors
Transverse sections of embryos treated with DMSO (A-F) or DAPT (G-L), visualized for kdrl:GFP ( and K) (green) and EphrinB2 (B, D, F, H, J and L) (red). Embryos were treated from 10 to 18 hpf (A-B, and G-H), from 10 to 14 hpf (C-D, and I-K), or from 14 to 18 hpf (E-F, and K-L). White dotted lines highlight the cell boundaries, and white arrowheads point to the expression of EphrinB2 within endothelial cells. DAPT treatment from 10 to 14 hpf leads to an increase in endothelial precursors, but does not affect EphrinB2 expression. Treatment from 14 to 18 hpf leads to a loss of EphrinB2 expression, but does not affect endothelial cell number.

Acknowledgments

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