Fig. S5 Neurons derived from URL are unaltered in Met signaling morphants. Lateral view (A–F) of phox2a expression in the locus coeruleus neurons (indicated by arrows) in control (A and D), Met morphants (B and E) and Hgf morphants (C and F) of 24 hpf (A–C) and 48 hpf (D–F) embryos. phox2a expression in neurons derived from the URL is unchanged in morphants compared to controls at 24 hpf, but there is a slight delay in the dorsal to ventral migration of these neurons. At 48 hpf, these neurons have completed their migration to the ventral hindbrain region in both controls and morphants. Scale bar, 50 μm.
Reprinted from Developmental Biology, 335(1), Elsen, G.E., Choi, L.Y., Prince, V.E., and Ho, R.K., The autism susceptibility gene met regulates zebrafish cerebellar development and facial motor neuron migration, 78-92, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.