ZFIN Image: Arrington et al., 2009, Fig. 5

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Figure Caption

Fig. 5 Extra-embryonic Sdc2 controls fibronectin polymerization. (A,B) Lateral and dorsal views of wild-type (A) and yolk^sdc2MO (B) embryos at the 12-somite stage. fibronectin 1 mRNA expression patterns were normal in yolk^sdc2MO embryos. (C) Western blot experiment showing normal accumulation of fibronectin (FN) protein monomers in wild-type and yolk^sdc2MO embryos. yolk^mtx1MO embryos have decreased fibronectin monomer accumulation due to decreased transcription of fibronectin 1 (Sakaguchi et al., 2006). α-tubulin (α Tub) was used as a loading control. (D-G) Lateral and dorsal views of wild-type (D,F) and yolk^sdc2MO (E,G) embryos at the 12-somite stage reveal similar expression patterns for mRNA encoding α5 integrin (D,E) and β1 integrin (F,G).

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Acknowledgments

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