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Fig. 9 Fgf signaling is activated in lmx1b morphant ocular regions. Whole mount in situ hybridization for fgf3 (A–D) and fgf8 (E–H) in control and lmx1bdMO embryos showing head (A, B, E, F) and higher magnification of the eyes (C, D, G, H). Note the expansion of fgf3 and fgf8 in optic stalk and ventral retinal tissues of lmx1bdMO embryos (solid arrows in panels B, F). In contrast, midbrain–hindbrain expression was decreased in lmx1bdMO morphant embryos (open arrows in panels B, F).
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Reprinted from Developmental Biology, 332(2), McMahon, C., Gestri, G., Wilson, S.W., and Link, B.A., Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish, 287-298, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.