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Figure Caption
Fig. S4
stat5.1 Morphants Show Long Muscle Fibers Extending through Somites
(A) Schematic representation of the stat5.1 gene showing the first three exons. The black line indicates normal splicing, while the red line highlights the abnormal splicing induced by the splice morpholino (pink).
(B–D) (B) Overview of WT embryo, (C) control morpholino injected embryo and (D) stat5.1 morphant. Muscles are labeled in green (αActin::GFP) and injected with lyndtTomato mRNA (red) at 34hpf. Arrowheads highlight the length of single muscle fibers, asterisks indicate gaps in somite boundaries.
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Reprinted from Developmental Cell, 16(2), Liu, Y.H., Jakobsen, J.S., Valentin, G., Amarantos, I., Gilmour, D.T., and Furlong, E.E., A Systematic Analysis of Tinman Function Reveals Eya and JAK-STAT Signaling as Essential Regulators of Muscle Development, 280-291, Copyright (2009) with permission from Elsevier. Full text @ Dev. Cell