ZFIN Image: Jin et al., 2009, Fig. S2

Image

Figure Caption

Fig. S2 Characterization of the runx1 null mutation W84X. (A) Schematic representation of Runx1 protein with runt homology domain marked and multispecies alignment of the region containing the mutation W84X shown by red box. A schematic of the predicted mutant protein is depicted underneath. Abbreviations: Dr, Danio rerio; Hs, Homo sapiens; Mm, Mus Musculus. (B-E) Whole-mount in situ hybridization of cmyb expression in 32 hpf wild-type (B), 32 hpf runx1^w84x mutant (C), 5 dpf wild-type (D) and 5 dpf runx1^w84x mutant (E) embryos. The insets are high magnification (20x) of the corresponding boxed regions (blue). Black arrow and arrowheads indicate cmyb expression in pronephros and PBI, respectively.

Acknowledgments

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