ZFIN Image: Miller-Bertoglio et al., 1999, Fig. 4

Image

Figure Caption

Fig. 4 ogo^m60 bmp4 expression domains are expanded in ogo mutant embryos. (A–C) Animal pole view with dorsal to the right. (A) The dorsal extent of bmp4 expression (arrowheads) was unaffected in 77% of embryos (70% epiboly) derived from ogo^m60 /+ intercrosses but was expanded in (B) the remaining 23%, presumed to be ogo^m60 /ogo^m60. (C) 100% of embryos from ogo^m60 /ogo^tm305 intercrosses displayed a dorsalward expansion of bmp4 expression. (D and E) Posterior views. Compared to their (D) WT siblings, bmp4 expression was highly expanded in the tailbuds of (E) ogo^m60 /ogo^m60 embryos (8 somites). At 20 somites, bmp4 was expressed in (F) the single ventral fin fold of WT embryos and (G) the multiple, ectopic fin folds (arrows) of ogo^m60 /ogo^m60 embryos. Scale bars, 200 μm.

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Reprinted from Developmental Biology, 214(1), Miller-Bertoglio, V., Carmany-Rampey, A., Fürthauer, M., Gonzalez, E.M., Thisse, C., Thisse, B., Halpern, M.E., and Solnica-Krezel, L., Maternal and zygotic activity of the zebrafish ogon locus antagonizes BMP signaling, 72-86, Copyright (1999) with permission from Elsevier. Full text @ Dev. Biol.