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Fig. 2
Blocking Notch Signalling Causes Somite Boundary Defects after a Long Delay
Embryos were treated with 100 μm DAPT or with DMSO (control) medium and stained by ISH for titin at the end of somitogenesis to reveal somite boundaries. Treatment was begun (A) at 3 hpf, (B) at 5-somite stage, or (C) at 9-somite stage. Arrows with grey labels indicate stage at onset of DAPT treament; arrows with black labels indicate the level of the earliest defective somite. A detailed view of the region where disruption begins is shown to the right of each DAPT specimen.
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