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Fig. S7 Wnt activation enhances liver regeneration in zebrafish. (A–L) Sagittal, H+E stained sections through adult zebrafish at 1, 3, and 5 dpr. APC+/- and hs:wnt8 fish demonstrate enhanced liver regeneration, while hs:dnTCF fish fail to regenerate liver. The vertical line in each panel indicates the resection margin. The horizontal arrow represents the extent of hepatic regrowth in the inferior lobe.
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Reprinted from Developmental Biology, 320(1), Goessling, W., North, T.E., Lord, A.M., Ceol, C., Lee, S., Weidinger, G., Bourque, C., Strijbosch, R., Haramis, A.P., Puder, M., Clevers, H., Moon, R.T., and Zon, L.I., APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development, 161-174, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.