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Fig. S2 Apoptotic cell death does not occur during early endoderm development in APC-/- mutants. (A-C) Whole mount TUNEL staining at 24 hpf revealed few apoptotic cells in wild-type and APC+/-- embryos. APC-/-- embryos demonstrate increased numbers of TUNEL positive cells, without massive apoptotic cell death in the endoderm at this stage.
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Reprinted from Developmental Biology, 320(1), Goessling, W., North, T.E., Lord, A.M., Ceol, C., Lee, S., Weidinger, G., Bourque, C., Strijbosch, R., Haramis, A.P., Puder, M., Clevers, H., Moon, R.T., and Zon, L.I., APC mutant zebrafish uncover a changing temporal requirement for wnt signaling in liver development, 161-174, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.