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Fig. 3 Hh signaling restricts cerebellar olig2 expression. Lateral (A, D) and dorsal (B, C, E, F) views of 48 hpf embryos with anterior to the left. Arrows indicate cerebellar olig2 expression. Brackets mark ventral spinal cord. (A) Wild-type embryo illustrating olig2 expression within cerebellum and spinal cord. Dorsal (B) and ventral (C) focal planes of wild-type cerebellum. (D–F) Similar views of olig2 expression in smo mutant embryo. Note expansion of cerebellar expression and absence of spinal cord expression. Scale bars represent 20 μm for all panels.
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Reprinted from Developmental Biology, 318(1), McFarland, K.A., Topczewska, J.M., Weidinger, G., Dorsky, R.I., and Appel, B., Hh and Wnt signaling regulate formation of olig2(+) neurons in the zebrafish cerebellum, 162-171, Copyright (2008) with permission from Elsevier. Full text @ Dev. Biol.