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Fig. S1 Manipulation of EphB. (A, B) Incubation of a brain in unclustered Ephrin-B2/Fc did not prevent habenular commissure formation (arrowhead). The ligand did bind to commissural axons, as indicated by Alexa 546 anti-Fc antibody (A). (B) Acetylated tubulin labeling, showing axon tracts. (C) An axon expressing truncated EphB3, fused to GFP (arrow). The axon is traversing the roof plate.
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Reprinted from Molecular and cellular neurosciences, 37(2), Hendricks, M., Mathuru, A.S., Wang, H., Silander, O., Kee, M.Z., and Jesuthasan, S., Disruption of Esrom and Ryk identifies the roof plate boundary as an intermediate target for commissure formation, 271-283, Copyright (2008) with permission from Elsevier. Full text @ Mol. Cell Neurosci.