ZFIN Image: Kozlowski et al., 2005, Fig. 7

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Figure Caption

Fig. 7 Time course of cell death in dog^tm90b. Single wild-type (A, C, E, and G) and dog^tm90b mutant (B, D, F, and H) embryos stained with acridine orange at 48 hpf (A–D) and 72 hpf (E and F). (A and B) dog^tm90b embryos show an increase in the number of acridine orange-positive cells in the otic vesicle (B) and migrating primordium of the posterior lateral line (D) relative to wild-type siblings (compare A, B and C, D). (E and F) The same wild-type sibling (E) and dog^tm90b (F) embryos as shown in the previous panels continue to exhibit an increased number of AO-positive cells at 46 hpf. (G and H) Otocyst phenotype of dog^tm90b (H) and wild-type sibling (G) embryos shown in (A, C, and E) and (B, D, and F), respectively. All panels: anterior to left, dorsal to top. Scale bar, 100μm.

Acknowledgments

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Reprinted from Developmental Biology, 277(1), Kozlowski, D.J., Whitfield, T.T., Hukriede, N.A., Lam, W.K., and Weinberg, E.S., The zebrafish dog-eared mutation disrupts eya1, a gene required for cell survival and differentiation in the inner ear and lateral line, 27-41, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.