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Fig. S2

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ZDB-IMAGE-071001-57
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Figures for van der Meer et al., 2006
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Fig. S2 Cypher RNA was injected at the 1 cell stage at the indicated concentrations. An uninjected control, as well as embryos injected with 50ng were indistinguishable to the 100ng embryos. All did not show a phenotype. 500ng injected embryos showed severe defects and malformations already at early stage (14hpf). Toxicity is a possible explanation, or a combination of a specific effect and toxicity since the phenotypes induced were very severe and rather heterologous.

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Reprinted from Developmental Biology, 299(2), van der Meer, D.L., Marques, I.J., Leito, J.T., Besser, J., Bakkers, J., Schoonheere, E., and Bagowski, C.P., Zebrafish cypher is important for somite formation and heart development, 356-372, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.