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Fig. 7 Laminin α1 and laminin α4 chains function redundantly during ISV sprouting. At 24 hpf, wild-type embryos (A) and bal mutant embryos injected with control MO (B) as well as wild-type embryos injected with lama4 MO (C) show normal fli-1 expression in both axial and intersegmental vessels. In contrast, bal mutants injected with lama4 MO (D) lack fli-1 staining of intersegmental vessels.
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Reprinted from Developmental Biology, 289(1), Pollard, S.M., Parsons, M.J., Kamei, M., Kettleborough, R.N., Thomas, K.A., Pham, V.N., Bae, M.K., Scott, A., Weinstein, B.M., and Stemple, D.L., Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation, 64-76, Copyright (2006) with permission from Elsevier. Full text @ Dev. Biol.