ZFIN Image: Miyake et al., 2005, Fig. 7

Image

Figure Caption

Fig. 7 Interactions between Fgf19, Fgf3 and Fgf8 in the forebrain and midbrain. (A–D) Embryos were injected with control Fgf19 MO (A and C), Fgf19 MO (B and D) at 25 hpf. In the Fgf19 MO-injected embryos, Fgf3 (A and B) and Fgf8 (C and D) were expressed normally in the MHB (arrows) but the expression of Fgf3 and Fgf8 was up-regulated in the forebrain (arrowheads). (E and F) Fgf19 expression in embryos injected with standard control MO (E), and Fgf3 MO and Fgf8 MO (F) at 25 hpf. (E) In the embryos injected with standard control MO, Fgf19 was normally expressed. (F) In the embryos injected with both Fgf3 MO and Fgf8 MO, Fgf19 expression in the forebrain was unaffected, while that in the midbrain (arrow) decreased. Lateral views with anterior to the left and dorsal to the top.

Figure Data

Expression / Labeling details

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 288(1), Miyake, A., Nakayama, Y., Konishi, M., and Itoh, N., Fgf19 regulated by Hh signaling is required for zebrafish forebrain development, 259-275, Copyright (2005) with permission from Elsevier. Full text @ Dev. Biol.