ZFIN Image: Hagos et al., 2007, Fig. 7

Image

Figure Caption

Fig. 7 Treatment with SB-505124 after MBT enhances the MZoep mutant phenotype. MZoep mutants were treated with DMSO (A, C), SB-431542 at the 16- to 32-cell stage (B), or SB-505124 at 3 hpf (D). The majority of MZoep mutants treated with DMSO develop long tails containing somites (A), but a minority has underdeveloped tails with no apparent somites (C). After treatment with SB-431542 during the cleavage stages, all MZoep mutants have shortened tails with no apparent somites (B). Similarly, MZoep mutants have short tails after treatment with SB-505124 at 3 hpf (D). Images of live embryos at 24 h, anterior to the left.

Acknowledgments

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Reprinted from Developmental Biology, 309(2), Hagos, E.G., Fan, X., and Dougan, S.T., The role of maternal Activin-like signals in zebrafish embryos, 245-258, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.