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Fig. 5 Expression of tbx5 and fibin in presumptive pectoral fin bud regions of gene knockdown or DEAB-treated embryos. The expression of tbx5 was examined in wild-type (a) and fibin-knockdown (b) presumptive pectoral fin bud regions at 26 hpf by whole mount in situ hybridization. The expression of fibin was examined in wild-type (c), tbx5-knockdown (d), wnt2b-knockdown (e) and DEAB-treated (f) presumptive pectoral fin bud regions at 18 hpf.
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Reprinted from Developmental Biology, 303(2), Wakahara, T., Kusu, N., Yamauchi, H., Kimura, I., Konishi, M., Miyake, A., and Itoh, N., fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish, 527-535, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.