ZFIN Image: Plaster et al., 2007, Fig. 8

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Figure Caption

Fig. 8 Histone deacetylase (HDAC) activity is required for proper Fgf signaling during development of the posterior mesoderm. A-D: Lateral views of live 26 hours postfertilization (hpf) wild-type (A,B) or ace (C,D) embryos, treated with either dimethylsulfoxide (DMSO) control medium (A,C) or 200 nM Trichostatin A (TSA, B,D) are shown. TSA-treated embryos are slightly delayed. The black arrow in D marks severely disrupted tail mesoderm, resembling the bab;ace phenotype at 24 hpf. E-H: Whole-mount in situ hybridizations (dorsal views on the tail bud) of papc at the four-somite stage in wild-type embryos (E,F) or ace (G,H) treated with DMSO control medium (E,G) or 200 nM TSA (F,H) from 30% epiboly.

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Acknowledgments

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